..Information on this page:
1) RESEARCH & TESTING IN THE 1950s
2) "PROCAINE" VITAMIN H3
3) Publications About GH3

RESEARCH & TESTING IN THE 1950s
Dr. Ana Aslan, M.D. spent 5 years researching and testing GH-3 as an anti-aging formula before announcing her findings in 1956. The test results were positive. GH-3 worked. One year later after more tests proved without a doubt that GH-3 is effective, Dr. Ana Aslan's findings were being tested by various countries around the world (GH-3, Will It Keep You Young Longer?", Herbert Bailey, Page 5). Today GH3 can be sold over the counter in England, Scotland, Wales, Northern Ireland, France, Italy, Germany, Brazil, Switzerland and many other highly progressive countries--over 70 in all.

TABLETS vs. INJECTABLES
Dr. Ana Aslan told me that the tablets were more effective in parts of the body other than the brain and central nervous system. GH-3 in tablet form apparently works better in the intestines to synthesize folic acid, Vitamin K, and Vitamin B-12, partly as a result of the breakdown of GH3 into PABA and DEAE. Both oral and injectable forms of GH3 pass the blood-brain barrier. Injectables enter the blood stream within seconds and are in the brain within half a minute. The therapeutic effect is exerted on the brain and central nervous system, and only later follows the circuitous path in various organs and tissues. ("GH3," Herbert Bailey, Page 109).

IS GH3 SAFE?
There are few substances on the market today which have undergone as much scientific testing as GH3. There are even fewer which have shown a comparable amount of positive results. Leading researchers have shown that GH3 is the safest and most effective anti-depressant ever tested. Dr. Nathan Kline, M.D., associate professor at Columbia University of Physicians and Surgeons made a study on the safety of GH3. Kline gave both humans and rats up to 60 times the optimum dose of GH3. Neither the rats nor the humans experienced any side effects. (GH3 Discovery, Jerome Godin, Pages 27 and 36).

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"PROCAINE"  VITAMIN H3

Procaine Hydrochloride was first synthesized in 1905 by a German chemist Albert Einhorn.  He was looking for a compound that would act as an anesthetic, would be non-toxic, free of side effects, and would not be addictive. 

Dr. Einhorn was looking for a compound that could replace cocaine as an anesthetic.  Cocaine was being used at the time as an anesthetic.  However, because cocaine was toxic, addictive, and destructive to the central nervous system, its use was being outlawed. 

Dr. Einhorn was able to produce a compound that demonstrated the properties he was looking for.  This new compound he named procaine.  "Pro" means, in place of, and "caine" comes from the word cocaine.  Because of the similarity of the names and because they are both anesthetics, there is much confusion as to the nature of procaine. 

Procaine when injected into the muscles acts as an anesthetic but when taken orally in a complexed form procaine acts as a vitamin.  Procaine HCl solutions, used as anesthetics, are trade named Novocaine.

Chemically procaine is the PABA ester of amino alcohol DEAE.  PABA (p-amino-benzoic acid) is a "B" vitamin.  DEAE, (n,n diethylaminoethanol) is biologically active precursor of the "B" vitamin choline. (Fig. 1) 

Procaine is usually used in the form of the hydrochloride salt (procaine HCl) because it is highly water-soluble.  Procaine hydrochloride, when taken orally, enters the body by being mainly absorbed through the villi in the small intestine. 

Experiments show that the bulk of the procaine HCl enters the bloodstream molecularly intact.  In the blood stream procaine HCl is rapidly hydrolyzed by the enzyme pseudo-cholinesterase into PABA and DEAE the two components of the procaine molecule.  These metabolites are removed by the liver, chemically changed, and excreted in the urine.

In the late 1940's Dr. Ana Aslan a Romanian cardiologist found that adding a small amount of benzoic acid to the procaine solution stabilized some of the procaine enough to protect it from the blood enzymes. 

This protected procaine, which Dr. Aslan named Gerovital H3 or GH-3 was found to be very helpful in supplying PABA and DEAE to damaged and or diseased cells.  Ana Aslan named the procaine vitamin H-3.  GH-3 is listed under H-3 in the Merck index.

Procaine HCl when combined with biologically active acids (1) such as folic acid, biotin, ascorbic acid, pantothenic acid, citric acid and many other acids such as amino acids etc. acts as a vitamin or food supplement.  The vitamin acids and other biologically active acids when complexed with the procaine HCl molecule protect the procaine from the enzymes in the blood allowing the procaine to enter the cells. 

These vitamin complexes help the cells assimilate and utilize nutrients more efficiently.  These complexed procaine compounds named Ultimate 9.

Procaine HCl (procaine hydrochloride) is the active ingredient in Dr Aslan's Gerovital H3 (GH-3) and Ultimate 9.

Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE.  The PABA and DEAE are rapidly conjugated and removed from the blood and excreted from the body.  Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to produce benefits.  Procaine HCl will produce some benefits by itself, but they are very limited. 

However when procaine HCl is complexed properly (1) the procaine HCl is protected from the action of the enzymes in the blood and tissues this protection gives the procaine enough time to be transferred into the cells of the body where it helps the cells to rebuild, repair, and detoxify.  This action of the procaine HCl complex is responsible for the remarkable improvements in health that result from the use of GH-3 and the Ultimate 9.

Many companies claim to make GH-3.  Based on my testing the only GH-3 procaine HCl based products that contain the active GH- factor or properly complexed procaine HCl are Ana Aslan's injectable GH-3 and Ultimate 9. 

Some companies are totally fraudulent in their claims quoting Ana Aslan case studies and my case studies and research to validate their products, which contain no procaine HCl, or its complexes. 

Their products contain PABA and DMAE which they claim produce procaine in the body.  This is false because procaine contains no DMAE (dimethylaminoethanol).  In fact the DMAE when it enters the cells of the body is broken down and is oxidized producing by products (metabolites) that are damaging and toxic to the cells (i.e. formaldehyde and methyl alcohol).  Whereas the DEAE (diethylaminoethanol) from the procaine HCl breaks down in the cells and is oxidized producing acetyl groups that are very valuable for producing acetylcholine and other materials necessary for cellular health.

Other companies produce GH-3 and similar products that contain procaine HCl and the other ingredients necessary to make GH-3 and Ultimate 9 and list them on their labels but they do not have a valid product.  They mix the dry ingredients together and tablet them or put them in capsules without first forming the procaine complexes.  Take the example of making the candy called fudge. 

Fudge contains sugar, cocoa, condensed milk, butter and a pinch of salt.  If you mix all these together you have the correct formula but you only have a gritty cocoa in canned milk with a chunk of butter far from being Fudge.  However if you cook the ingredients to the soft ball stage and then allow it to cool, then beat it properly to the right crystalline structure you end up with a delicious delight called fudge.

The procaine HCl complexes must be formed or the product won't be very effective in helping cells heal and overcome their problems. 

Effective procaine products in tablets or capsules containing complexed procaine will show on the labels not only the correct ingredients but they will also show the patent numbers (1) of the process for forming the complexes of procaine found in Ultimate 9.

(1) U.S. Patent Nos.  5,283,258, 5,254,686, 5,283,068, 5162,344. Australian patent Nos. 332917, 046241  Canadian patent No. 2,012,021

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Publications About GH3
 

MAGAZINE ARTICLES

1) "Stay Young Longer," Living Magazine
2) "GH3," Alternative Health Magazine
3) "Rumanian Rejuvenation," from Secrets of Life Extension by John A. Mann
4) "Controversial Treatment Lures Thousands," National Geographic
5) "Encouraging Results Seen in GH3 Use by 41 Patients, Internal Medicine News Service
6) "Unlocking the Secrets of the Fountain of Youth," Better Living
7) "Adding Years to Your Life," Doris Whitehead
8) "Youth Regained," The Body Forum
9) "Gerovital Comes In from the Cold," Medical World News
10) Additional GH3 Articles found in Psychology Today, Mc Calls, and Newsweek
11) "Dr. Aslan and GH3," Denver Newsletter, October, 1977
12) "Health and Longevity Secrets From Rumania," Worldwide Secrets For Staying Young
13) "Is Aging Reversal Possible With GH3?", New York Times

PUBLISHED BOOKS ON GH3

1)"GH3", a comprehensive history study of GH3 by medical investigative journalist, Herbert Bailey. A Bantam Book (ISBN 0-553-14460-X) Bantam Books, Inc., New York. (Or write directly to Mr. Herbert Bailey, P.O. Box 636, Sandy Hook, CT 06482. Or contact Bantam Books, New York.

2)"GEROVITAL H3". by Dr. Ana Aslan, M.D., Phoenix Creation Ltd., 810 West Broadway, Suite 396, Vancouver, B.C. V5Z1J8

3)"GEROVITAL H3 IN THE BATTLE AGAINST AGE". by Dr. R. Marx

4)"GEROVITAL H3, THE ROAD TO DISCOVERY". by Jerome Godin

5)"THE BATTLE AGAINST DEPRESSION WITH GEROVITAL H3", -- Dr. Allan Sapse, M.D.

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